Gene: PVT1

Basic information

LNCipedia gene ID: PVT1 
Location (hg19): chr8:128806769-129200457
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA_gene
Transcripts: 83

Transcripts

Transcript IDLocation (hg19)Length
PVT1:1 chr8:128806769-129113334 1200 bp
PVT1:10 chr8:128806803-128867565 343 bp
PVT1:11 chr8:128806803-128867565 458 bp
PVT1:12 chr8:128806803-128952700 1535 bp
PVT1:13 chr8:128806806-128951855 392 bp
PVT1:14 chr8:128806821-128903198 938 bp
PVT1:15 chr8:128808000-128903178 599 bp
PVT1:16 chr8:128808059-128903041 568 bp
PVT1:17 chr8:128808066-128903206 624 bp
PVT1:18 chr8:128808279-128903229 844 bp
PVT1:19 chr8:128866974-128902987 221 bp
PVT1:2 chr8:128806769-128944943 855 bp
PVT1:20 chr8:128867394-128944934 806 bp
PVT1:21 chr8:128867394-128944934 1218 bp
PVT1:22 chr8:128875961-129021884 1561 bp
PVT1:23 chr8:128902874-129113499 1699 bp
PVT1:24 chr8:128902892-128944941 584 bp
PVT1:25 chr8:128902923-129008896 542 bp
PVT1:26 chr8:128903116-129008896 518 bp
PVT1:27 chr8:128988494-129007177 230 bp
PVT1:28 chr8:128994696-129007177 209 bp
PVT1:29 chr8:128996266-129009287 796 bp
PVT1:3 chr8:128806769-129113334 1536 bp
PVT1:30 chr8:128996419-129007177 211 bp
PVT1:31 chr8:129000923-129004320 1836 bp
PVT1:32 chr8:129001430-129082518 383 bp
PVT1:33 chr8:129001463-129108824 408 bp
PVT1:34 chr8:129001507-129108902 922 bp
PVT1:35 chr8:129021904-129113343 443 bp
PVT1:36 chr8:129082403-129113473 498 bp
PVT1:37 chr8:129082409-129113491 602 bp
PVT1:38 chr8:129082568-129112144 706 bp
PVT1:39 chr8:129094933-129113503 577 bp
PVT1:4 chr8:128806779-128903221 754 bp
PVT1:40 chr8:129096767-129113488 501 bp
PVT1:41 chr8:129096767-129113488 705 bp
PVT1:42 chr8:129103340-129113488 660 bp
PVT1:43 chr8:129103340-129113488 864 bp
PVT1:44 chr8:129108059-129113473 390 bp
PVT1:45 chr8:129108765-129112133 654 bp
PVT1:46 chr8:129111318-129113488 620 bp
PVT1:47 chr8:129111598-129113429 426 bp
PVT1:48 chr8:129111755-129113486 326 bp
PVT1:49 chr8:128806787-128867565 359 bp
PVT1:5 chr8:128806779-129113498 1900 bp
PVT1:50 chr8:128806787-128867565 474 bp
PVT1:51 chr8:128806787-128903198 972 bp
PVT1:52 chr8:128806787-128903221 746 bp
PVT1:53 chr8:128806787-128914778 681 bp
PVT1:54 chr8:128806787-128952700 1551 bp
PVT1:55 chr8:128806787-128951855 411 bp
PVT1:56 chr8:128808068-128808274 207 bp
PVT1:57 chr8:128808068-128903206 622 bp
PVT1:58 chr8:128808068-129113502 1933 bp
PVT1:59 chr8:128808068-128903041 559 bp
PVT1:6 chr8:128806800-129113502 5132 bp
PVT1:60 chr8:128808068-128903229 1055 bp
PVT1:61 chr8:128808068-128966214 710 bp
PVT1:62 chr8:128808068-129085675 1125 bp
PVT1:63 chr8:128808068-128903178 531 bp
PVT1:64 chr8:128902867-128914794 471 bp
PVT1:65 chr8:128902867-128944372 452 bp
PVT1:66 chr8:128902867-128944941 609 bp
PVT1:67 chr8:128902867-129113499 1706 bp
PVT1:68 chr8:128902867-129008896 598 bp
PVT1:69 chr8:128944297-128951753 7191 bp
PVT1:7 chr8:128806802-129011472 2164 bp
PVT1:70 chr8:128988202-128994377 2371 bp
PVT1:71 chr8:128988202-129113508 1262 bp
PVT1:72 chr8:128988202-129007230 575 bp
PVT1:73 chr8:128988202-129011683 999 bp
PVT1:74 chr8:128988202-129113508 893 bp
PVT1:75 chr8:128996144-129022690 13144 bp
PVT1:76 chr8:128996144-129085675 666 bp
PVT1:77 chr8:128996144-129113508 1113 bp
PVT1:78 chr8:128996144-129113508 970 bp
PVT1:79 chr8:128996144-129200457 19273 bp
PVT1:8 chr8:128806802-129113334 1221 bp
PVT1:80 chr8:129009322-129010438 1117 bp
PVT1:81 chr8:129061655-129085675 569 bp
PVT1:82 chr8:129061655-129125827 13079 bp
PVT1:83 chr8:128806779-129113499 1940 bp
PVT1:9 chr8:128806802-129113334 1334 bp


Locus conservation

Locus conservation?
PVT1 no no no no

Available literature

  1. Austin (2017), Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle., J. Allergy Clin. Immunol.
  2. Cui (2016), Long non-coding RNA PVT1 as a novel biomarker for diagnosis and prognosis of non-small cell lung cancer., Tumour Biol.
  3. Li (2016), Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells., Nucleic Acids Res.
  4. Zhou (2016), Long noncoding RNA PVT1 modulates thyroid cancer cell proliferation by recruiting EZH2 and regulating thyroid-stimulating hormone receptor (TSHR)., Tumour Biol.
  5. Cabanski (2015), Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function., RNA Biol
  6. Colombo (2015), PVT1: a rising star among oncogenic long noncoding RNAs., Biomed Res Int
  7. Ding (2015), Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients., Oncol Lett
  8. Guo (2015), Competing endogenous RNA networks and gastric cancer., World J. Gastroenterol.
  9. Huang (2015), Increased expression of the lncRNA PVT1 is associated with poor prognosis in pancreatic cancer patients., Minerva Med.
  10. Kim (2015), MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression., Oncotarget
  11. Kong (2015), Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16., Mol. Cancer
  12. Liu (2015), Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1., Int J Clin Exp Pathol
  13. Malouf (2015), Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing., Mol Oncol
  14. Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., Int J Clin Exp Med
  15. Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., Int J Clin Exp Med
  16. Ragusa (2015), Non-coding landscapes of colorectal cancer., World J. Gastroenterol.
  17. Shih (2015), Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism., Int J Mol Sci
  18. Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
  19. Wei (2015), Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor., Oncotarget
  20. Xue (2015), Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma., Int J Clin Exp Pathol
  21. Younger (2015), Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage., Nucleic Acids Res.
  22. Yu (2015), Cardiac hypertrophy is positively regulated by long non-coding RNA PVT1., Int J Clin Exp Pathol
  23. Zeng (2015), Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia., J Hematol Oncol
  24. Zhang (2015), Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance., Biochem. Biophys. Res. Commun.
  25. Zhang (2015), Cancer Specific Long Noncoding RNAs Show Differential Expression Patterns and Competing Endogenous RNA Potential in Hepatocellular Carcinoma., PLoS ONE
  26. Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Sci Rep
  27. Zhuang (2015), Tetracycline-inducible shRNA targeting long non-coding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells., Oncotarget
  28. Alaimo (2014), ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference., Front Bioeng Biotechnol
  29. Athie (2014), FAL1ing inside an amplicon., Cancer Cell
  30. Chinen (2014), 8q24 amplified segments involve novel fusion genes between NSMCE2 and long noncoding RNAs in acute myelogenous leukemia., J Hematol Oncol
  31. Ding (2014), Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer., Onco Targets Ther
  32. Dryden (2014), Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C., Genome Res.
  33. Garzon (2014), Expression and prognostic impact of lncRNAs in acute myeloid leukemia., Proc. Natl. Acad. Sci. U.S.A.
  34. Johnsson (2014), Expanding the functional role of long noncoding RNAs., Cell Res.
  35. Kim (2014), Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis., Oncogene
  36. Li (2014), Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Front Bioeng Biotechnol
  37. Paci (2014), Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer., BMC Syst Biol
  38. Perry (2014), Role of non-coding RNAs in maintaining primary airway smooth muscle cells., Respir. Res.
  39. Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
  40. Takahashi (2014), Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers., Br. J. Cancer
  41. Tseng (2014), PVT1 dependence in cancer with MYC copy-number increase., Nature
  42. Wan (2014), Noncoding RNAs in DNA repair and genome integrity., Antioxid. Redox Signal.
  43. Wang (2014), Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2., Hepatology
  44. Wang (2014), Characteristics of PVT1 and its roles in diseases., Chin. Med. Sci. J.
  45. Yang (2014), A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases., PLoS ONE
  46. Yang (2014), Increased expression of the lncRNA PVT1 promotes tumorigenesis in non-small cell lung cancer., Int J Clin Exp Pathol
  47. Zhang (2014), Frequent mutation of rs13281615 and its association with PVT1 expression and cell proliferation in breast cancer., J Genet Genomics
  48. Alvarez (2013), Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy., PLoS ONE
  49. Bisio (2013), Identification of new p53 target microRNAs by bioinformatics and functional analysis., BMC Cancer
  50. Cao (2013), Analysis of long non-coding RNA expression profiles in gastric cancer., World J. Gastroenterol.
  51. Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
  52. Alvarez (2011), Functional characterization of the plasmacytoma variant translocation 1 gene (PVT1) in diabetic nephropathy., PLoS ONE
  53. You (2011), Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells., Biochem. Biophys. Res. Commun.
  54. Carramusa (2007), The PVT-1 oncogene is a Myc protein target that is overexpressed in transformed cells., J. Cell. Physiol.