Transcript: DANCR:8

Basic information

LNCipedia transcript ID: DANCR:8 
HGNC Gene Symbol: DANCR    
HGNC Full Gene Name: differentiation antagonizing non-protein coding RNA
Ensembl Gene ID: ENSG00000226950
Ensembl Transcript ID: ENST00000441504
Location (hg19): chr4:53578665-53579296
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 336 bp
Exons: 2
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000441504; ENST00000441504.1; DANCR-003; OTTHUMT00000336532.1; NONHSAT096373
Alternative gene names: ENSG00000226950; KIAA0114; ENSG00000226950.2; DANCR; OTTHUMG00000154670.1; ENSG00000226950.6; ANCR; AGU2; lncRNA-ANCR


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 1 non-coding 
PhyloCSF score non-coding 
CPAT coding probability 7.84% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
DANCR:8 no no no no

Available literature

  1. Chen (2016), lncRNA DANCR suppresses odontoblast-like differentiation of human dental pulp cells by inhibiting wnt/β-catenin pathway., Cell Tissue Res.
  2. Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
  3. Yuan (2016), Long noncoding RNA DANCR increases stemness features of hepatocellular carcinoma by derepression of CTNNB1., Hepatology
  4. Jia (2015), Down-regulated non-coding RNA (lncRNA-ANCR) promotes osteogenic differentiation of periodontal ligament stem cells., Arch. Oral Biol.
  5. Liu (2015), Over-expression of lncRNA DANCR is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer., Int J Clin Exp Pathol
  6. Lopez-Pajares (2015), A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation., Dev. Cell
  7. Tong (2015), Long non-coding RNA-DANCR in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis., Biosci. Biotechnol. Biochem.
  8. Zhang (2015), Whole transcriptome microarrays identify long non-coding RNAs associated with cardiac hypertrophy., Genom Data
  9. Hart (2014), MYC regulates the non-coding transcriptome., Oncotarget
  10. Munschauer (2014), High-resolution profiling of protein occupancy on polyadenylated RNA transcripts., Methods
  11. Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
  12. van Heesch (2014), Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes., Genome Biol.
  13. Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
  14. Kretz (2013), Control of somatic tissue differentiation by the long non-coding RNA TINCR., Nature
  15. Zhu (2013), Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression., Biochem. Biophys. Res. Commun.
  16. Kretz (2012), Suppression of progenitor differentiation requires the long noncoding RNA ANCR., Genes Dev.
  17. Kikuchi (2009), Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation., Nucleic Acids Res.
  18. Nagase (1995), Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1., DNA Res.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-RASL11B-2:2
3.1 lnc-RASL11B-3:2
4.0 DANCR:8
4.1 DANCR:8
5.0 DANCR:8
5.1 DANCR:8
5.2 DANCR:8