Transcript: GAS5:22

Basic information

LNCipedia transcript ID: GAS5:22 
HGNC Gene Symbol: GAS5    
HGNC Full Gene Name: growth arrest specific 5
Ensembl Gene ID: ENSG00000234741
Ensembl Transcript ID: ENST00000454068
Location (hg19): chr1:173833049-173836953
Strand: -
Class: bidirectional
Sequence Ontology term:
Transcript size: 688 bp
Exons: 12
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000454068; ENST00000454068.1; GAS5-014; OTTHUMT00000090590.1; NONHSAT007681; ENST00000454068.5
Alternative gene names: ENSG00000234741; GAS5; ENSG00000234741.2; OTTHUMG00000037216.2; ENSG00000234741.3; ENSG00000234741.7; SNHG2; NCRNA00030


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -100.5817 non-coding 
CPAT coding probability 1.33% non-coding 
Bazzini small ORFs 1 coding 
covF1Prop0.645833333
seqAAMVLGADAVWLWIAPYGQLCPQGRMRIATEVLKSKPNSSHWHTGIRQKAGS
orfFrame11.1131472

In stringent set: no

Locus conservation

Locus conservation?
GAS5:22 no no no no

Available literature

  1. Chang (2016), Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin., Mol Med Rep
  2. Fayda (2016), Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?, Tumour Biol.
  3. Han (2016), Circulating long noncoding RNA GAS5 as a potential biomarker in breast cancer for assessing the surgical effects., Tumour Biol.
  4. Hu (2016), Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21., Tumour Biol.
  5. Ma (2016), The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers., Tumour Biol.
  6. Thorenoor (2016), Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer., Oncotarget
  7. Bo (2015), Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma., Oncotarget
  8. Cabili (2015), Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution., Genome Biol.
  9. Cai (2015), Long noncoding RNA CCAT2 promotes breast tumor growth by regulating the Wnt signaling pathway., Onco Targets Ther
  10. Carter (2015), Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus., BBA Clin


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-SERPINC1-1:15
3.1 lnc-SERPINC1-1:15
4.0 GAS5:22
4.1 GAS5:22
5.0 GAS5:22
5.1 GAS5:22
5.2 GAS5:22

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