Transcript: GNAS-AS1:4

Basic information

LNCipedia transcript ID: GNAS-AS1:4 
HGNC Gene Symbol: GNAS-AS1    
HGNC Full Gene Name: GNAS antisense RNA 1
Ensembl Gene ID: ENSG00000235590
Ensembl Transcript ID: ENST00000424094
Location (hg19): chr20:57393974-57425958
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 1156 bp
Exons: 5
Sources: Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000424094.2; ENST00000424094.6
Alternative gene names: ENSG00000235590.3; GNAS-AS1; ENSG00000235590.7; SANG; NESP-AS; NESPAS; GNAS1AS; NCRNA00075


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -65.553 non-coding 
CPAT coding probability 16.49% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
GNAS-AS1:4 yes no no no

Available literature

  1. Kanduri (2016), Long noncoding RNAs: Lessons from genomic imprinting., Biochim. Biophys. Acta
  2. He (2015), LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis., Bioinformatics
  3. Lertampaiporn (2014), Identification of non-coding RNAs with a new composite feature in the Hybrid Random Forest Ensemble algorithm., Nucleic Acids Res.
  4. Takahashi (2014), Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer., FEBS Open Bio
  5. Kobayashi (2013), Epigenetic and transcriptional features of the novel human imprinted lncRNA GPR1AS suggest it is a functional ortholog to mouse Zdbf2linc., Epigenetics
  6. Chillambhi (2010), Deletion of the noncoding GNAS antisense transcript causes pseudohypoparathyroidism type Ib and biparental defects of GNAS methylation in cis., J. Clin. Endocrinol. Metab.
  7. Zhao (2010), Genome-wide identification of polycomb-associated RNAs by RIP-seq., Mol. Cell
  8. Williamson (2006), Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster., Nat. Genet.
  9. Williamson (2002), Alternative non-coding splice variants of Nespas, an imprinted gene antisense to Nesp in the Gnas imprinting cluster., Mamm. Genome
  10. Hayward (2000), An imprinted antisense transcript at the human GNAS1 locus., Hum. Mol. Genet.
  11. Li (2000), Tissue-specific expression of antisense and sense transcripts at the imprinted Gnas locus., Genomics
  12. Wroe (2000), An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus., Proc. Natl. Acad. Sci. U.S.A.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-CTSZ-3:2
4.0 GNAS-AS1:4
4.1 GNAS-AS1:4
5.0 GNAS-AS1:4
5.1 GNAS-AS1:4
5.2 GNAS-AS1:4