Transcript: HOTAIR:10
Basic information
LNCipedia transcript ID: HOTAIR:10
HGNC Gene Symbol: HOTAIR
HGNC Full Gene Name:
HOX transcript antisense RNA
Ensembl Gene ID:
ENSG00000228630
Ensembl Transcript ID:
ENST00000425595
Location (hg19): chr12:54357586-54360414
Strand: -
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 572 bp
Exons: 4
Sources: Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000425595; ENST00000425595.1; HOTAIR-005; OTTHUMT00000328666.1; NONHSAT028513; ENST00000425595.5
Alternative gene names: ENSG00000228630; HOTAIR; ENSG00000228630.1; OTTHUMG00000152934.1; ENSG00000228630.5; HOXC-AS4; HOXC11-AS1; NCRNA00072
RNA sequence:
Structure:
Protein coding potential
In stringent set: yes
Locus conservation
| Locus conservation? |  |
 |
 |
 |
|---|---|---|---|---|
| HOTAIR:10 | no | no | no | no |
Available literature
- Botti (2017), LncRNA HOTAIR as Prognostic Circulating Marker and Potential Therapeutic Target in Patients with Tumor Diseases., Curr Drug Targets
- Bayram (2016), A functional HOTAIR rs12826786 C>T polymorphism is associated with breast cancer susceptibility and poor clinicopathological characteristics in a Turkish population: a hospital-based case-control study., Tumour Biol.
- Bhan (2016), Estradiol-Induced Transcriptional Regulation of Long Non-Coding RNA, HOTAIR., Methods Mol. Biol.
- Chang (2016), Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin., Mol Med Rep
- Choudhry (2016), Hypoxic regulation of the noncoding genome and NEAT1., Brief Funct Genomics
- Fang (2016), Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells., Lab. Invest.
- Fayda (2016), Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?, Tumour Biol.
- Fu (2016), Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways., Oncotarget
- Gao (2016), ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer., Oncotarget
- Jiang (2016), The long non-coding RNA HOTAIR affects the radiosensitivity of pancreatic ductal adenocarcinoma by regulating the expression of Wnt inhibitory factor 1., Tumour Biol.
- Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
- Li (2016), Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer., Tumour Biol.
- Liu (2016), Epigenetic silencing of p21 by long non-coding RNA HOTAIR is involved in the cell cycle disorder induced by cigarette smoke extract., Toxicol. Lett.
- Liu (2016), The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster., Nucleic Acids Res.
- Mohankumar (2016), Extracellular vesicle long noncoding RNA as potential biomarkers of liver cancer., Brief Funct Genomics
- Pan (2016), A functional lncRNA HOTAIR genetic variant contributes to gastric cancer susceptibility., Mol. Carcinog.
- Sun (2016), Involvement of lncRNA dysregulation in gastric cancer., Histol. Histopathol.
- Thorenoor (2016), Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer., Oncotarget
- Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget
- Xue (2016), LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer., Oncogene
- Yang (2016), Knockdown of long non-coding RNA HOTAIR inhibits proliferation and invasiveness and improves radiosensitivity in colorectal cancer., Oncol. Rep.
- Zhang (2016), Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology., J. Clin. Pathol.
- Abba (2015), A Molecular Portrait of High-Grade Ductal Carcinoma In Situ., Cancer Res.
- Bayram (2015), Effect of HOTAIR rs920778 polymorphism on breast cancer susceptibility and clinicopathologic features in a Turkish population., Tumour Biol.
- Bayram (2015), A functional HOTAIR rs920778 polymorphism does not contributes to gastric cancer in a Turkish population: a case-control study., Fam. Cancer
- Bhan (2015), LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer., Biochim. Biophys. Acta
- Cabanski (2015), Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function., RNA Biol
- Carter (2015), Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus., BBA Clin
- Chen (2015), Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells., Cell. Physiol. Biochem.
- Chen (2015), SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma., Sci Rep
- Chen (2015), Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity., Sci Rep
- Chen (2015), Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA., Sci Rep
- Chen (2015), Radiotherapy induced Lewis lung cancer cell apoptosis via inactivating β-catenin mediated by upregulated HOTAIR., Int J Clin Exp Pathol
- Cheng (2015), The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration., Oncotarget
- Chillón (2015), Native Purification and Analysis of Long RNAs., Meth. Enzymol.
- Conigliaro (2015), CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA., Mol. Cancer
- Dang (2015), Expression and clinical significance of long non-coding RNA HNF1A-AS1 in human gastric cancer., World J Surg Oncol
- Ding (2015), Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients., Oncol Lett
- Ding (2015), Long non-coding RNA Loc554202 induces apoptosis in colorectal cancer cells via the caspase cleavage cascades., J. Exp. Clin. Cancer Res.
- Du (2015), The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population., Oncotarget
- Díaz-Beyá (2015), The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature., Oncotarget
- Fan (2015), Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis., Genome Biol.
- Fan (2015), Erratum to: Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis., Genome Biol.
- Fang (2015), Probing Xist RNA Structure in Cells Using Targeted Structure-Seq., PLoS Genet.
- Fiscon (2015), MONSTER v1.1: a tool to extract and search for RNA non-branching structures., BMC Genomics
- Fu (2015), Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling., J. Hepatol.
- Gaiti (2015), Dynamic and Widespread lncRNA Expression in a Sponge and the Origin of Animal Complexity., Mol. Biol. Evol.
- Gan (2015), Focusing on long noncoding RNA dysregulation in gastric cancer., Tumour Biol.
- Gandhy (2015), Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC., Oncotarget
- Ge (2015), MiRNA-192 [corrected] and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma., PLoS Genet.
- Guerrieri (2015), Long non-coding RNAs era in liver cancer., World J Hepatol
- Guo (2015), Associations between polymorphisms of HOTAIR and risk of gastric cardia adenocarcinoma in a population of north China., Tumour Biol.
- Guo (2015), Competing endogenous RNA networks and gastric cancer., World J. Gastroenterol.
- Guo (2015), Comprehensive analysis of lncRNA-mRNA co-expression patterns identifies immune-associated lncRNA biomarkers in ovarian cancer malignant progression., Sci Rep
- Gökmen-Polar (2015), Prognostic impact of HOTAIR expression is restricted to ER-negative breast cancers., Sci Rep
- Hajjari (2015), HOTAIR: an oncogenic long non-coding RNA in different cancers., Cancer Biol Med
- Hao (2015), Prediction of long noncoding RNA functions with co-expression network in esophageal squamous cell carcinoma., BMC Cancer
- Hao (2015), HOTAIR is upregulated in acute myeloid leukemia and that indicates a poor prognosis., Int J Clin Exp Pathol
- Heubach (2015), The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells., Mol. Cancer
- Hu (2015), A common set of distinct features that characterize noncoding RNAs across multiple species., Nucleic Acids Res.
- Hu (2015), Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma., J. Exp. Clin. Cancer Res.
- Hu (2015), Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813., Int J Clin Exp Pathol
- Hu (2015), NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2., Oncotarget
- Hua (2015), High expression of long non-coding RNA ANRIL is associated with poor prognosis in hepatocellular carcinoma., Int J Clin Exp Pathol
- Huang (2015), HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma., Oncotarget
- Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Sci Rep
- Iyer (2015), The landscape of long noncoding RNAs in the human transcriptome., Nat. Genet.
- Jiang (2015), LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data., BMC Genomics
- Jiang (2015), Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations., Oncotarget
- Jiang (2015), Novel insights into a treatment for aplastic anemia based on the advanced proliferation of bone marrow‑derived mesenchymal stem cells induced by fibroblast growth factor 1., Mol Med Rep
- Jiao (2015), Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line., Oncol Lett
- Jing (2015), HOTAIR enhanced aggressive biological behaviors and induced radio-resistance via inhibiting p21 in cervical cancer., Tumour Biol.
- Ke (2015), Knockdown of long non-coding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR-326., Oncotarget
- Kim (2015), Long non-coding RNA HOTAIR is associated with human cervical cancer progression., Int. J. Oncol.
- Kim (2015), Genome-wide transcript profiling reveals novel breast cancer-associated intronic sense RNAs., PLoS ONE
- Kong (2015), Targeting HOTAIR Induces Mitochondria Related Apoptosis and Inhibits Tumor Growth in Head and Neck Squamous Cell Carcinoma in vitro and in vivo., Curr. Mol. Med.
- Koufariotis (2015), A catalogue of novel bovine long noncoding RNA across 18 tissues., PLoS ONE
- Li (2015), Expression of the long non-coding RNAs MEG3, HOTAIR, and MALAT-1 in non-functioning pituitary adenomas and their relationship to tumor behavior., Pituitary
- Li (2015), A high level of circulating HOTAIR is associated with progression and poor prognosis of cervical cancer., Tumour Biol.
- Li (2015), MDR1 will play a key role in pharmacokinetic changes under hypoxia at high altitude and its potential regulatory networks., Drug Metab. Rev.
- Li (2015), Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population., Oncotarget
- Li (2015), Expression of long non-coding RNA DLX6-AS1 in lung adenocarcinoma., Cancer Cell Int.
- Li (2015), Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer., Diagn Pathol
- Li (2015), Prognostic role of HOTAIR in four estrogen-dependent malignant tumors: a meta-analysis., Onco Targets Ther
- Li (2015), LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2., Oncotarget
- Li (2015), LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns., Oncotarget
- Li (2015), Erratum to: Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer., Tumour Biol.
- Liu (2015), Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract., Toxicol. Appl. Pharmacol.
- Liu (2015), Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1., Int J Clin Exp Pathol
- Liu (2015), Over-expression of lncRNA DANCR is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer., Int J Clin Exp Pathol
- Ma (2015), Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of human lincRNA genes., Nat. Methods
- Malouf (2015), Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing., Mol Oncol
- Martínez-Fernández (2015), Analysis of the Polycomb-related lncRNAs HOTAIR and ANRIL in bladder cancer., Clin Epigenetics
- Martínez-Fernández (2015), EZH2 in Bladder Cancer, a Promising Therapeutic Target., Int J Mol Sci
- Na (2015), Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway., Int J Clin Exp Med
- Nie (2015), Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression., Mol. Cancer Ther.
- Nwigwe (2015), Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions., PLoS ONE
- Oliver (2015), Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype., Cereb. Cortex
- Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proc. Natl. Acad. Sci. U.S.A.
- Pedram Fatemi (2015), Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen., J Biomol Screen
- Pei (2015), Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5., Int J Clin Exp Med
- Peng (2015), Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression., J. Exp. Clin. Cancer Res.
- Peschansky (2015), Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells., Front Genet
- Qiu (2015), The long non-coding RNA HOTAIR promotes the proliferation of serous ovarian cancer cells through the regulation of cell cycle arrest and apoptosis., Exp. Cell Res.
- Qiu (2015), A novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27., Cell Death Dis
- Quek (2015), lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs., Nucleic Acids Res.
- Ragusa (2015), Non-coding landscapes of colorectal cancer., World J. Gastroenterol.
- Richards (2015), A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer., Oncotarget
- Rupaimoole (2015), Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis., Cell Rep
- Scarola (2015), Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA., Nat Commun
- Sharma (2015), Bridging Links between Long Noncoding RNA HOTAIR and HPV Oncoprotein E7 in Cervical Cancer Pathogenesis., Sci Rep
- Shen (2015), Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival., Cancers (Basel)
- Shi (2015), Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis., Int J Clin Exp Pathol
- Shi (2015), Microvascular invasion in hepatocellular carcinoma overexpression promotes cell proliferation and inhibits cell apoptosis of hepatocellular carcinoma via inhibiting miR-199a expression., Onco Targets Ther
- Silva (2015), The Clinical Relevance of Long Non-Coding RNAs in Cancer., Cancers (Basel)
- Smolle (2015), Long Non-Coding RNAs in Endometrial Carcinoma., Int J Mol Sci
- Somarowthu (2015), HOTAIR forms an intricate and modular secondary structure., Mol. Cell
- Song (2015), PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritis., Clin. Exp. Med.
- Song (2015), Long non-coding RNA HOTAIR promotes HLA-G expression via inhibiting miR-152 in gastric cancer cells., Biochem. Biophys. Res. Commun.
- Sugihara (2015), Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma., Int J Mol Sci
- Sun (2015), Increased expression of lncRNA HULC indicates a poor prognosis and promotes cell metastasis in osteosarcoma., Int J Clin Exp Pathol
- Sun (2015), Long non-coding RNA HOTAIR regulates cyclin J via inhibition of microRNA-205 expression in bladder cancer., Cell Death Dis
- Sun (2015), A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients., Sci Rep
- Tan (2015), Reprogramming during epithelial to mesenchymal transition under the control of TGFβ., Cell Adh Migr
- Tan (2015), HOTAIR inhibited intracellular Ca2+ via regulation of Cav1.2 channel in human cardiomyocytes., Cell. Mol. Biol. (Noisy-le-grand)
- Tantai (2015), Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer., Int J Clin Exp Pathol
- Teschendorff (2015), HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer., Genome Med
- Tong (2015), Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma., Mol. Cancer
- Wang (2015), Overexpression of Long Non-Coding RNA HOTAIR Promotes Tumor Growth and Metastasis in Human Osteosarcoma., Mol. Cells
- Wang (2015), Prognostic value of long noncoding RNA HOTAIR in digestive system malignancies., J. Gastroenterol. Hepatol.
- Wang (2015), Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition., Cancer Cell Int.
- Wang (2015), Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR., Oncotarget
- Wang (2015), Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection., Proc. Natl. Acad. Sci. U.S.A.
- Wang (2015), Genome-scale long noncoding RNA expression pattern in squamous cell lung cancer., Sci Rep
- Wang (2015), LncRNA NALT interaction with NOTCH1 promoted cell proliferation in pediatric T cell acute lymphoblastic leukemia., Sci Rep
- Wang (2015), Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma., Int J Clin Exp Med
- Wang (2015), LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer., Oncotarget
- Wang (2015), The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH., Sci Rep
- Wang (2015), Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma., PLoS ONE
- Wei (2015), Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor., Oncotarget
- Werner (2015), Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes., Cell Rep
- Wongtrakoongate (2015), Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes., PLoS Genet.
- Wu (2015), The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma., Oncotarget
- Wu (2015), Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma., Int. J. Oncol.
- Wu (2015), Expression of long noncoding RNA-HOX transcript antisense intergenic RNA in oral squamous cell carcinoma and effect on cell growth., Tumour Biol.
- Wu (2015), Overexpression of long non-coding RNA HOTAIR predicts a poor prognosis in patients with acute myeloid leukemia., Oncol Lett
- Xie (2015), Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression., Oncotarget
- Xing (2015), Long non-coding RNA HOTAIR modulates c-KIT expression through sponging miR-193a in acute myeloid leukemia., FEBS Lett.
- Xue (2015), Genetic variants in lncRNA HOTAIR are associated with risk of colorectal cancer., Mutagenesis
- Xue (2015), Genome-wide analysis of long noncoding RNA signature in human colorectal cancer., Gene
- Xue (2015), Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma., Int J Clin Exp Pathol
- Yamamoto (2015), Breast Cancer: Radiogenomic Biomarker Reveals Associations among Dynamic Contrast-enhanced MR Imaging, Long Noncoding RNA, and Metastasis., Radiology
- Yan (2015), Prognostic significance of long non-coding RNA PCAT-1 expression in human hepatocellular carcinoma., Int J Clin Exp Pathol
- Yan (2015), Polymorphisms in lncRNA HOTAIR and susceptibility to breast cancer in a Chinese population., Cancer Epidemiol
- Yang (2015), Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway., Cell. Physiol. Biochem.
- Yang (2015), Expression profile of long non-coding RNAs is altered in endometrial cancer., Int J Clin Exp Med
- Yang (2015), High MALAT1 expression predicts a poor prognosis of cervical cancer and promotes cancer cell growth and invasion., Eur Rev Med Pharmacol Sci
- Ye (2015), Evaluation of four genetic variants in han chinese subjects with high myopia., J Ophthalmol
- Ye (2015), Enhancing HOTAIR/MiR-10b Drives Normal Liver Stem Cells Toward a Tendency to Malignant Transformation Through Inducing Epithelial- to-Mesenchymal Transition., Rejuvenation Res
- Ye (2015), Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance., Int J Clin Exp Med
- Yin (2015), SnoVectors for nuclear expression of RNA., Nucleic Acids Res.
- Yin (2015), Expression Quantitative Trait Loci for CARD8 Contributes to Risk of Two Infection-Related Cancers--Hepatocellular Carcinoma and Cervical Cancer., PLoS ONE
- Yu (2015), Long non-coding RNAs and hepatocellular carcinoma., Mol Clin Oncol
- Yu (2015), Long noncoding RNAs in hepatitis B virus-related hepatocellular carcinoma., World J. Gastroenterol.
- Yu (2015), Long non-coding RNA HOTAIR: A novel oncogene (Review)., Mol Med Rep
- Yu (2015), Long non-coding RNA growth arrest-specific transcript 5 in tumor biology., Oncol Lett
- Zhai (2015), Long noncoding RNA MALAT1 as a putative biomarker of lymph node metastasis: a meta-analysis., Int J Clin Exp Med
- Zhang (2015), Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner., Oncotarget
- Zhang (2015), HOTAIR Long Noncoding RNA Promotes Gastric Cancer Metastasis through Suppression of Poly r(C)-Binding Protein (PCBP) 1., Mol. Cancer Ther.
- Zhang (2015), PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis., Cancer Res.
- Zhang (2015), Circulating DNA of HOTAIR in serum is a novel biomarker for breast cancer., Breast Cancer Res. Treat.
- Zhang (2015), LncRNA MALAT1 overexpression is an unfavorable prognostic factor in human cancer: evidence from a meta-analysis., Int J Clin Exp Med
- Zhang (2015), LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer., Cell Rep
- Zhang (2015), Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value., Biomed Res Int
- Zhang (2015), Overexpression of long non-coding RNA CCAT1 is a novel biomarker of poor prognosis in patients with breast cancer., Int J Clin Exp Pathol
- Zhang (2015), Molecular mechanism of HEIH and HULC in the proliferation and invasion of hepatoma cells., Int J Clin Exp Med
- Zhao (2015), Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer., Cell Cycle
- Zhao (2015), HOTAIR is a predictive and prognostic biomarker for patients with advanced gastric adenocarcinoma receiving fluorouracil and platinum combination chemotherapy., Am J Transl Res
- Zheng (2015), Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells., Mol. Cell Proteomics
- Zhou (2015), Long noncoding RNA HOTAIR, a hypoxia-inducible factor-1α activated driver of malignancy, enhances hypoxic cancer cell proliferation, migration, and invasion in non-small cell lung cancer., Tumour Biol.
- Zhou (2015), Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer., Sci Rep
- Zhou (2015), Long Non Coding RNA MALAT1 Promotes Tumor Growth and Metastasis by inducing Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma., Sci Rep
- Zhu (2015), [Effects of long non-coding RNA-HOTAIR on the cell cycle and invasiveness of prostate cancer]., Zhonghua Nan Ke Xue
- Zhu (2015), Ectopic expressed long non-coding RNA H19 contributes to malignant cell behavior of ovarian cancer., Int J Clin Exp Pathol
- Zhuang (2015), Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells., Mol. Carcinog.
- Zou (2015), [Long noncoding RNA HOTAIR modulates the function of trophoblast cells in pre-eclampsia]., Sichuan Da Xue Xue Bao Yi Xue Ban
- Alaimo (2014), ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference., Front Bioeng Biotechnol
- Almlöf (2014), Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes., PLoS ONE
- Barnhill (2014), High expression of CAI2, a 9p21-embedded long noncoding RNA, contributes to advanced-stage neuroblastoma., Cancer Res.
- Basu (2014), Using amino-labeled nucleotide probes for simultaneous single molecule RNA-DNA FISH., PLoS ONE
- Bhan (2014), Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo., J. Steroid Biochem. Mol. Biol.
- Brunner (2014), A shared transcriptional program in early breast neoplasias despite genetic and clinical distinctions., Genome Biol.
- Cai (2014), Long noncoding RNA HOTAIR can serve as a common molecular marker for lymph node metastasis: a meta-analysis., Tumour Biol.
- Cai (2014), HOTAIR: a cancer-related long non-coding RNA., Neoplasma
- Cao (2014), [Genome wide screening and characterization of long non-coding RNAs in esophageal cancer]., Zhonghua Yi Xue Yi Chuan Xue Za Zhi
- Carrion (2014), The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes., PLoS ONE
- Chakravadhanula (2014), Expression of the HOX genes and HOTAIR in atypical teratoid rhabdoid tumors and other pediatric brain tumors., Cancer Genet
- Chen (2014), Cisplatin and paclitaxel target significant long noncoding RNAs in laryngeal squamous cell carcinoma., Med. Oncol.
- Chi (2014), Role of BC040587 as a predictor of poor outcome in breast cancer., Cancer Cell Int.
- Chiyomaru (2014), Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells., J. Biol. Chem.
- Cifuentes-Rojas (2014), Regulatory interactions between RNA and polycomb repressive complex 2., Mol. Cell
- Cogill (2014), Co-expression Network Analysis of Human lncRNAs and Cancer Genes., Cancer Inform
- Collier (2014), Regulation of the Th1 genomic locus from Ifng through Tmevpg1 by T-bet., J. Immunol.
- Davidovich (2014), A dimeric state for PRC2., Nucleic Acids Res.
- Deng (2014), Up-regulation of 91H promotes tumor metastasis and predicts poor prognosis for patients with colorectal cancer., PLoS ONE
- Deng (2014), Prognostic value of long non-coding RNA HOTAIR in various cancers., PLoS ONE
- Ding (2014), Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells., Int J Mol Sci
- Ding (2014), Long intergenic non-coding RNAs (LincRNAs) identified by RNA-seq in breast cancer., PLoS ONE
- Ding (2014), Expression of long non-coding RNA LOC285194 and its prognostic significance in human pancreatic ductal adenocarcinoma., Int J Clin Exp Pathol
- Divoux (2014), Identification of a novel lncRNA in gluteal adipose tissue and evidence for its positive effect on preadipocyte differentiation., Obesity (Silver Spring)
- Dryden (2014), Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C., Genome Res.
- Emadi-Andani (2014), Association of HOTAIR expression in gastric carcinoma with invasion and distant metastasis., Adv Biomed Res
- Feng (2014), Methods for the study of long noncoding RNA in cancer cell signaling., Methods Mol. Biol.
- Garzon (2014), Expression and prognostic impact of lncRNAs in acute myeloid leukemia., Proc. Natl. Acad. Sci. U.S.A.
- Gezer (2014), Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes., Cell Biol. Int.
- Guallar (2014), RNA-binding proteins in pluripotency, differentiation, and reprogramming., Front Biol (Beijing)
- Guo (2014), BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition., Oncol Lett
- Halley (2014), Regulation of the apolipoprotein gene cluster by a long noncoding RNA., Cell Rep
- Han (2014), A long noncoding RNA protects the heart from pathological hypertrophy., Nature
- Han (2014), LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition., BMC Cancer
- He (2014), The long non-coding RNA HOTAIR is upregulated in endometrial carcinoma and correlates with poor prognosis., Int. J. Mol. Med.
- Hou (2014), Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients., PLoS ONE
- Hu (2014), A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer., Cancer Cell
- Huang (2014), Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancer., Arch. Gynecol. Obstet.
- Huang (2014), Lentivirus-mediated RNA interference targeting the long noncoding RNA HOTAIR inhibits proliferation and invasion of endometrial carcinoma cells in vitro and in vivo., Int. J. Gynecol. Cancer
- Hudson (2014), Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate., Nat Commun
- Isin (2014), Investigation of circulating lncRNAs in B-cell neoplasms., Clin. Chim. Acta
- Jiang (2014), LncRNA: a new player in 1α, 25(OH)(2) vitamin D(3) /VDR protection against skin cancer formation., Exp. Dermatol.
- Jiang (2014), The role of MALAT1 correlates with HPV in cervical cancer., Oncol Lett
- Kim (2014), Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5., Proc. Natl. Acad. Sci. U.S.A.
- Kretz (2014), RNA binding of PRC2: promiscuous or well ordered?, Mol. Cell
- Lau (2014), Viral-human chimeric transcript predisposes risk to liver cancer development and progression., Cancer Cell
- Lee (2014), Long non-coding RNA HOTAIR promotes carcinogenesis and invasion of gastric adenocarcinoma., Biochem. Biophys. Res. Commun.
- Li (2014), starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data., Nucleic Acids Res.
- Li (2014), A new Lnc in metastasis: long noncoding RNA mediates the prometastatic functions of TGF-β., Cancer Cell
- Li (2014), A polymorphism rs12325489C>T in the lincRNA-ENST00000515084 exon was found to modulate breast cancer risk via GWAS-based association analyses., PLoS ONE
- Li (2014), Comparison of long non‑coding RNAs, microRNAs and messenger RNAs involved in initiation and progression of esophageal squamous cell carcinoma., Mol Med Rep
- Li (2014), Long non-coding RNA BANCR promotes proliferation in malignant melanoma by regulating MAPK pathway activation., PLoS ONE
- Li (2014), Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis., Breast Cancer Res.
- Li (2014), Long noncoding RNA GHET1 promotes the development of bladder cancer., Int J Clin Exp Pathol
- Li (2014), [Long noncoding RNAs in gene expression control]., Zhong Nan Da Xue Xue Bao Yi Xue Ban
- Li (2014), Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation., RNA Biol
- Li (2014), Overexpression of long non-coding RNA UCA1 predicts a poor prognosis in patients with esophageal squamous cell carcinoma., Int J Clin Exp Pathol
- Lin (2014), Long noncoding RNA expression in dermal papilla cells contributes to hairy gene regulation., Biochem. Biophys. Res. Commun.
- Liu (2014), Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer., Mol. Cancer
- Liu (2014), LncRNAs expression signatures of hepatocellular carcinoma revealed by microarray., World J. Gastroenterol.
- Liu (2014), Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression., J. Natl. Cancer Inst.
- Loewen (2014), Functions of lncRNA HOTAIR in lung cancer., J Hematol Oncol
- Ma (2014), Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer., Mol. Cancer
- Malek (2014), Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer., Oncotarget
- Mathiyalagan (2014), Interplay of chromatin modifications and non-coding RNAs in the heart., Epigenetics
- Mazar (2014), The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells., Oncotarget
- Mehra (2014), A novel RNA in situ hybridization assay for the long noncoding RNA SChLAP1 predicts poor clinical outcome after radical prostatectomy in clinically localized prostate cancer., Neoplasia
- Negishi (2014), A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins., PLoS ONE
- Okugawa (2014), Metastasis-associated long non-coding RNA drives gastric cancer development and promotes peritoneal metastasis., Carcinogenesis
- Ono (2014), Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer., Cancer Med
- Pei (2014), Influence of curcumin on HOTAIR-mediated migration of human renal cell carcinoma cells., Asian Pac. J. Cancer Prev.
- Pestell (2014), Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo., Asian J. Androl.
- Peter (2014), Identification of differentially expressed long noncoding RNAs in bladder cancer., Clin. Cancer Res.
- Pircher (2014), Ribosome-associated ncRNAs: an emerging class of translation regulators., RNA Biol
- Porro (2014), TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres., Cell Rep
- Puvvula (2014), Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit., Nat Commun
- Qin (2014), Expression pattern of long non-coding RNAs in renal cell carcinoma revealed by microarray., PLoS ONE
- Qiu (2014), Overexpression of long non-coding RNA HOTAIR predicts poor patient prognosis and promotes tumor metastasis in epithelial ovarian cancer., Gynecol. Oncol.
- Quinn (2014), Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification., Nat. Biotechnol.
- Quinodoz (2014), Long noncoding RNAs: an emerging link between gene regulation and nuclear organization., Trends Cell Biol.
- Roberts (2014), The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
- Seki (2014), A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells., PLoS ONE
- Song (2014), A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis., J. Orthop. Res.
- Su (2014), Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes., Oncotarget
- Sun (2014), A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies., Nucleic Acids Res.
- Svoboda (2014), HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients., Carcinogenesis
- Takahashi (2014), Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer., FEBS Open Bio
- Takahashi (2014), Widespread genome transcription: new possibilities for RNA therapies., Biochem. Biophys. Res. Commun.
- Tong (2014), Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma., J Transl Med
- Tu (2014), Down-regulation of long non-coding RNA GAS5 is associated with the prognosis of hepatocellular carcinoma., Int J Clin Exp Pathol
- Wan (2014), Aberrantly expressed long noncoding RNAs in human intervertebral disc degeneration: a microarray related study., Arthritis Res. Ther.
- Wang (2014), Exploring the stability of long intergenic non-coding RNA in K562 cells by comparative studies of RNA-Seq datasets., Biol. Direct
- Wang (2014), Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma., Med. Oncol.
- White (2014), Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer., Genome Biol.
- Wright (2014), A short guide to long non-coding RNA gene nomenclature., Hum. Genomics
- Wu (2014), Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer., Oncol. Rep.
- Wu (2014), Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells., Tumour Biol.
- Wu (2014), Long noncoding RNA HOTAIR involvement in cancer., Tumour Biol.
- Xie (2014), NONCODEv4: exploring the world of long non-coding RNA genes., Nucleic Acids Res.
- Xing (2014), Identification of long noncoding RNA associated with osteoarthritis in humans., Orthop Surg
- Xu (2014), Long non-coding RNA URHC regulates cell proliferation and apoptosis via ZAK through the ERK/MAPK signaling pathway in hepatocellular carcinoma., Int. J. Biol. Sci.
- Xu (2014), Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis., PLoS ONE
- Xu (2014), Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expression., J Hematol Oncol
- Xu (2014), Long non-coding RNA LSINCT5 predicts negative prognosis and exhibits oncogenic activity in gastric cancer., Medicine (Baltimore)
- Yan (2014), Upregulation of the long noncoding RNA HOTAIR predicts recurrence in stage Ta/T1 bladder cancer., Tumour Biol.
- Yang (2014), Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency., Elife
- Yang (2014), Osteopontin enhances the expression of HOTAIR in cancer cells via IRF1., Biochim. Biophys. Acta
- Yao (2014), Large intervening non-coding RNA HOTAIR is an indicator of poor prognosis and a therapeutic target in human cancers., Int J Mol Sci
- Yarmishyn (2014), HOXD-AS1 is a novel lncRNA encoded in HOXD cluster and a marker of neuroblastoma progression revealed via integrative analysis of noncoding transcriptome., BMC Genomics
- You (2014), Long noncoding RNA HOX transcript antisense intergenic RNA (HOTAIR) as a foe and novel potential therapeutic target for endometrial carcinoma., Int. J. Gynecol. Cancer
- Zhang (2014), Long non-coding RNA HOTAIR in carcinogenesis and metastasis., Acta Biochim. Biophys. Sin. (Shanghai)
- Zhang (2014), The identification of an ESCC susceptibility SNP rs920778 that regulates the expression of lncRNA HOTAIR via a novel intronic enhancer., Carcinogenesis
- Zhang (2014), MiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway., Stem Cells
- Zhang (2014), Long noncoding RNA HOTAIR as an independent prognostic marker in cancer: a meta-analysis., PLoS ONE
- Zhang (2014), Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers., BMC Genomics
- Zhao (2014), Role of HOTAIR long noncoding RNA in metastatic progression of lung cancer., Eur Rev Med Pharmacol Sci
- Zhao (2014), A novel wnt regulatory axis in endometrioid endometrial cancer., Cancer Res.
- Zhao (2014), Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications., Sci Rep
- Zhou (2014), The molecular mechanism of HOTAIR in tumorigenesis, metastasis, and drug resistance., Acta Biochim. Biophys. Sin. (Shanghai)
- Alaei-Mahabadi (2013), Limited evidence for evolutionarily conserved targeting of long non-coding RNAs by microRNAs., Silence
- Amort (2013), Long non-coding RNAs as targets for cytosine methylation., RNA Biol
- Arita (2013), Circulating long non-coding RNAs in plasma of patients with gastric cancer., Anticancer Res.
- Batagov (2013), Role of genomic architecture in the expression dynamics of long noncoding RNAs during differentiation of human neuroblastoma cells., BMC Syst Biol
- Beato (2013), A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes., Transcription
- Bhan (2013), Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol., J. Mol. Biol.
- Bhartiya (2013), lncRNome: a comprehensive knowledgebase of human long noncoding RNAs., Database (Oxford)
- Bhattacharjee (2013), Combinatorial control of gene expression., Biomed Res Int
- Bird (2013), Genome biology: not drowning but waving., Cell
- Cao (2013), Integrated analysis of long noncoding RNA and coding RNA expression in esophageal squamous cell carcinoma., Int J Genomics
- Chen (2013), LncRNADisease: a database for long-non-coding RNA-associated diseases., Nucleic Acids Res.
- Chen (2013), Upregulation of the long non-coding RNA HOTAIR promotes esophageal squamous cell carcinoma metastasis and poor prognosis., Mol. Carcinog.
- Chiyomaru (2013), Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR., PLoS ONE
- Cui (2013), [Expression of long non-coding RNA HOTAIR mRNA in ovarian cancer]., Sichuan Da Xue Xue Bao Yi Xue Ban
- Dasen (2013), Long noncoding RNAs in development: solidifying the Lncs to Hox gene regulation., Cell Rep
- Davidovich (2013), Promiscuous RNA binding by Polycomb repressive complex 2., Nat. Struct. Mol. Biol.
- Dodd (2013), Digital quantitation of potential therapeutic target RNAs., Nucleic Acid Ther
- Du (2013), Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer., Nat. Struct. Mol. Biol.
- Endo (2013), Enhanced expression of long non-coding RNA HOTAIR is associated with the development of gastric cancer., PLoS ONE
- Eun (2013), The Igf2/H19 muscle enhancer is an active transcriptional complex., Nucleic Acids Res.
- Ge (2013), HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF-1 expression and activates Wnt pathway., Cancer Sci.
- Hajjari (2013), Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues., Med. Oncol.
- Hangauer (2013), Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs., PLoS Genet.
- Holdt (2013), Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks., PLoS Genet.
- Ishibashi (2013), Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma., Oncol. Rep.
- Jalali (2013), Systematic transcriptome wide analysis of lncRNA-miRNA interactions., PLoS ONE
- Juan (2013), Potential roles of microRNAs in regulating long intergenic noncoding RNAs., BMC Med Genomics
- Kim (2013), HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer., Oncogene
- Lai (2013), Activating RNAs associate with Mediator to enhance chromatin architecture and transcription., Nature
- Li (2013), Long intergenic noncoding RNA HOTAIR is overexpressed and regulates PTEN methylation in laryngeal squamous cell carcinoma., Am. J. Pathol.
- Li (2013), Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma., Br. J. Cancer
- Li (2013), Targeted disruption of Hotair leads to homeotic transformation and gene derepression., Cell Rep
- Li (2013), Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer., J. Exp. Clin. Cancer Res.
- Ling (2013), MicroRNAs and other non-coding RNAs as targets for anticancer drug development., Nat Rev Drug Discov
- Liu (2013), Downregulation of GAS5 promotes bladder cancer cell proliferation, partly by regulating CDK6., PLoS ONE
- Liu (2013), The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer., BMC Cancer
- Liu (2013), The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression., PLoS ONE
- Lu (2013), Computational prediction of associations between long non-coding RNAs and proteins., BMC Genomics
- Lu (2013), Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression., BMC Cancer
- Luco (2013), The non-coding genome: a universe in expansion for fine-tuning the coding world., Genome Biol.
- Luo (2013), Upregulated H19 contributes to bladder cancer cell proliferation by regulating ID2 expression., FEBS J.
- Lv (2013), Long noncoding RNA HOTAIR is a prognostic marker for esophageal squamous cell carcinoma progression and survival., PLoS ONE
- Mudge (2013), Functional transcriptomics in the post-ENCODE era., Genome Res.
- Nakagawa (2013), Large noncoding RNA HOTAIR enhances aggressive biological behavior and is associated with short disease-free survival in human non-small cell lung cancer., Biochem. Biophys. Res. Commun.
- Nie (2013), Long non-coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival., Cancer Sci.
- Niemczyk (2013), Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA., Am. J. Hum. Genet.
- Papait (2013), Long noncoding RNA: a new player of heart failure?, J Cardiovasc Transl Res
- Prensner (2013), The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex., Nat. Genet.
- Pádua Alves (2013), Brief report: The lincRNA Hotair is required for epithelial-to-mesenchymal transition and stemness maintenance of cancer cell lines., Stem Cells
- Qi (2013), Low expression of LOC285194 is associated with poor prognosis in colorectal cancer., J Transl Med
- Qiu (2013), Long noncoding RNA: an emerging paradigm of cancer research., Tumour Biol.
- Rapicavoli (2013), A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics., Elife
- Redis (2013), CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations., Oncotarget
- Sánchez (2013), Long non-coding RNAs: challenges for diagnosis and therapies., Nucleic Acid Ther
- Sørensen (2013), Long non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor-positive primary breast cancer., Breast Cancer Res. Treat.
- Takayama (2013), Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer., EMBO J.
- Tang (2013), Long noncoding RNAs-related diseases, cancers, and drugs., ScientificWorldJournal
- Tang (2013), Long noncoding RNA HOTAIR is associated with motility, invasion, and metastatic potential of metastatic melanoma., Biomed Res Int
- Vallot (2013), Long non-coding RNAs and human X-chromosome regulation: a coat for the active X chromosome., RNA Biol
- Venkatesh (2013), Non-coding transcription SETs up regulation., Cell Res.
- Volders (2013), LNCipedia: a database for annotated human lncRNA transcript sequences and structures., Nucleic Acids Res.
- Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
- Wang (2013), EZH2 takes the stage when BRCA1 loses., Cell Cycle
- Wu (2013), Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma., Gastroenterology
- Wu (2013), A genetic polymorphism in lincRNA-uc003opf.1 is associated with susceptibility to esophageal squamous cell carcinoma in Chinese populations., Carcinogenesis
- Wu (2013), Ets-2 regulates cell apoptosis via the Akt pathway, through the regulation of urothelial cancer associated 1, a long non-coding RNA, in bladder cancer cells., PLoS ONE
- Wu (2013), Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins., Biochemistry
- Xu (2013), Knockdown of long non-coding RNA HOTAIR suppresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancer., Int. J. Biol. Sci.
- Yoon (2013), Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination., Nat Commun
- Zhang (2013), Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis., Asian Pac. J. Cancer Prev.
- Zhang (2013), HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma., Neuro-oncology
- Zhao (2013), HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells., J. Cell. Biochem.
- Zhuang (2013), Induction of long intergenic non-coding RNA HOTAIR in lung cancer cells by type I collagen., J Hematol Oncol
- Zou (2013), Upregulation of long noncoding RNA SPRY4-IT1 modulates proliferation, migration, apoptosis, and network formation in trophoblast cells HTR-8SV/neo., PLoS ONE
- Özgür (2013), Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells., Clin. Exp. Med.
- Augoff (2012), miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer., Mol. Cancer
- Brunner (2012), Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers., Genome Biol.
- Bánfai (2012), Long noncoding RNAs are rarely translated in two human cell lines., Genome Res.
- Chisholm (2012), Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma., PLoS ONE
- Chu (2012), Chromatin isolation by RNA purification (ChIRP)., J Vis Exp
- Du (2012), Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18., J. Biol. Chem.
- Flockhart (2012), BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration., Genome Res.
- Glazko (2012), Computational prediction of polycomb-associated long non-coding RNAs., PLoS ONE
- Gong (2012), Biochemical analysis of long non-coding RNA-containing ribonucleoprotein complexes., Methods
- Jeggari (2012), miRcode: a map of putative microRNA target sites in the long non-coding transcriptome., Bioinformatics
- Kelley (2012), Transposable elements reveal a stem cell-specific class of long noncoding RNAs., Genome Biol.
- Li (2012), AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and trans., Proc. Natl. Acad. Sci. U.S.A.
- Lu (2012), Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer., Breast Cancer Res. Treat.
- Maruyama (2012), Altered antisense-to-sense transcript ratios in breast cancer., Proc. Natl. Acad. Sci. U.S.A.
- Mizutani (2012), Identification and characterization of novel genotoxic stress-inducible nuclear long noncoding RNAs in mammalian cells., PLoS ONE
- Nagy (2012), [Relevance of long non-coding RNAs in tumour biology]., Orv Hetil
- Nakagawa (2012), Malat1 is not an essential component of nuclear speckles in mice., RNA
- Nam (2012), Long noncoding RNAs in C. elegans., Genome Res.
- Ng (2012), Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors., EMBO J.
- Niazi (2012), Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3' UTRs., RNA
- Niinuma (2012), Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors., Cancer Res.
- Ren (2012), RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings., Cell Res.
- Sati (2012), Genome-wide analysis reveals distinct patterns of epigenetic features in long non-coding RNA loci., Nucleic Acids Res.
- Talkowski (2012), Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities., Am. J. Hum. Genet.
- Tani (2012), Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals., Genome Res.
- Troy (2012), Genetic "lnc"-age of noncoding RNAs to human disease., J. Clin. Invest.
- Vizoso (2012), The activatory long non-coding RNA DBE-T reveals the epigenetic etiology of facioscapulohumeral muscular dystrophy., Cell Res.
- Wilusz (2012), HuR and translation--the missing linc(RNA)., Mol. Cell
- Bright (2011), Noncoding RNA, antigenic variation, and the virulence genes of Plasmodium falciparum., BMC Biol.
- Chan (2011), Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection., PLoS ONE
- Chu (2011), Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions., Mol. Cell
- Derrien (2011), [Long non-coding RNAs with enhancer-like function in human cells]., Med Sci (Paris)
- He (2011), The sequence, structure and evolutionary features of HOTAIR in mammals., BMC Evol. Biol.
- Kogo (2011), Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers., Cancer Res.
- Kotake (2011), Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene., Oncogene
- Milhem (2011), Correlation of MTDH/AEG-1 and HOTAIR Expression with Metastasis and Response to Treatment in Sarcoma Patients., J Cancer Sci Ther
- Nakagawa (2011), eXIST with matrix-associated proteins., Trends Cell Biol.
- Paralkar (2011), A new 'Linc' between noncoding RNAs and blood development., Genes Dev.
- Rose (2011), Molecular evolution of the non-coding eosinophil granule ontogeny transcript., Front Genet
- Saxena (2011), Long non-coding RNA modifies chromatin: epigenetic silencing by long non-coding RNAs., Bioessays
- Schorderet (2011), Structural and functional differences in the long non-coding RNA hotair in mouse and human., PLoS Genet.
- Simon (2011), The genomic binding sites of a noncoding RNA., Proc. Natl. Acad. Sci. U.S.A.
- Tahira (2011), Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer., Mol. Cancer
- Wang (2011), Molecular mechanisms of long noncoding RNAs., Mol. Cell
- Xin (2011), Identification and characterization of wheat long non-protein coding RNAs responsive to powdery mildew infection and heat stress by using microarray analysis and SBS sequencing., BMC Plant Biol.
- Yang (2011), Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation., Ann. Surg. Oncol.
- Zong (2011), RNA splicing control: yet another gene regulatory role for long nuclear noncoding RNAs., RNA Biol
- Gupta (2010), Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis., Nature
- Tsai (2010), Long noncoding RNA as modular scaffold of histone modification complexes., Science
- Khalil (2009), Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression., Proc. Natl. Acad. Sci. U.S.A.
- Rinn (2007), Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs., Cell
- Woo (2007), HOTAIR lifts noncoding RNAs to new levels., Cell
LNCipedia transcript ID history
| LNCipedia version | LNCipedia transcript ID |
|---|---|
| 1.3 | lnc-SMUG1-3:5 |
| 3.1 | lnc-SMUG1-7:5 |
| 4.0 | HOTAIR:10 |
| 4.1 | HOTAIR:10 |
| 5.0 | HOTAIR:10 |
| 5.1 | HOTAIR:10 |
| 5.2 | HOTAIR:10 |