Transcript: lnc-LRR1-1:1

Basic information

LNCipedia transcript ID: lnc-LRR1-1:1 
LNCipedia gene ID: lnc-LRR1-1
Ensembl Gene ID: ENSG00000283029
Ensembl Transcript ID: ENST00000635274
Location (hg19): chr14:50053297-50053596
Strand: +
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 300 bp
Exons: 1
Sources: long non-coding rna db - lncrnadb.com; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000553637.1; RN7SL1-001; OTTHUMT00000414196.1; NONHSAT036719; ENST00000635274.1
Alternative gene names: 7SL; 7S RNA; SRP RNA; 4.5S SRP RNA; 4.5S RNA; RN7SL1 RNA; ENSG00000258486.1; RN7SL1; OTTHUMG00000171559.1; ENSG00000258486.2; ENSG00000283029.1; AL139099.5; AL139099.4


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score 0.1046 non-coding 
CPAT coding probability 5.98% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
lnc-LRR1-1:1 yes no no no

Available literature

  1. Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
  2. Alaimo (2014), ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference., Front Bioeng Biotechnol
  3. Kang (2014), HuD regulates coding and noncoding RNA to induce APP→Aβ processing., Cell Rep
  4. Abdelmohsen (2013), Senescence-associated lncRNAs: senescence-associated long noncoding RNAs., Aging Cell
  5. Castle (2010), Digital genome-wide ncRNA expression, including SnoRNAs, across 11 human tissues using polyA-neutral amplification., PLoS ONE
  6. Keene (2010), 7SL RNA is retained in HIV-1 minimal virus-like particles as an S-domain fragment., J. Virol.
  7. Zhang (2008), Demonstration of a multistep mechanism for assembly of the SRP x SRP receptor complex: implications for the catalytic role of SRP RNA., J. Mol. Biol.
  8. Siu (2007), SRP RNA provides the physiologically essential GTPase activation function in cotranslational protein targeting., RNA
  9. Wang (2007), 7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G., J. Virol.
  10. Zwieb (2005), A nomenclature for all signal recognition particle RNAs., RNA
  11. Kuglstatter (2002), Induced structural changes of 7SL RNA during the assembly of human signal recognition particle., Nat. Struct. Biol.
  12. Bhuiyan (2000), Assembly of archaeal signal recognition particle from recombinant components., Nucleic Acids Res.
  13. Peluso (2000), Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor., Science
  14. Stuart (2000), The 3' UTR of human MnSOD mRNA hybridizes to a small cytoplasmic RNA and inhibits gene expression., Biochem. Biophys. Res. Commun.
  15. Labuda (1994), Evolution of secondary structure in the family of 7SL-like RNAs., J. Mol. Evol.
  16. Quentin (1994), Emergence of master sequences in families of retroposons derived from 7sl RNA., Genetica
  17. Bernstein (1993), Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog., Proc. Natl. Acad. Sci. U.S.A.
  18. Sakamoto (1991), Modulation of HeLa cell growth by transfected 7SL RNA and Alu gene sequences., J. Biol. Chem.
  19. Kleinert (1988), Differential regulation of transcription of human 7 S K and 7 S L RNA genes., J. Biol. Chem.
  20. Ullu (1984), Human genes and pseudogenes for the 7SL RNA component of signal recognition particle., EMBO J.
  21. Ullu (1984), Alu sequences are processed 7SL RNA genes., Nature
  22. Walter (1983), Subcellular distribution of signal recognition particle and 7SL-RNA determined with polypeptide-specific antibodies and complementary DNA probe., J. Cell Biol.
  23. Li (1982), Nucleotide sequence of 7 S RNA. Homology to Alu DNA and La 4.5 S RNA., J. Biol. Chem.
  24. Walter (1982), Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum., Nature
  25. Zieve (1977), Synthesis of two classes of small RNA species in vivo and in vitro., Biochemistry


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-LRR1-1:1
3.1 lnc-LRR1-1:1
4.0 lnc-LRR1-1:1
4.1 lnc-LRR1-1:1
5.0 lnc-LRR1-1:1
5.1 lnc-AP5M1-123:3
5.2 lnc-LRR1-1:1