Gene: TUG1

Basic information

LNCipedia gene ID: TUG1 
Location (hg19): chr22:31365144-31381211
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA_gene
Transcripts: 76

Transcripts

Transcript IDLocation (hg19)Length
TUG1:1 chr22:31365144-31369578 3191 bp
TUG1:10 chr22:31365634-31375377 7101 bp
TUG1:11 chr22:31365634-31375298 7153 bp
TUG1:12 chr22:31365643-31374831 6477 bp
TUG1:13 chr22:31365698-31375382 7167 bp
TUG1:14 chr22:31365698-31375382 7028 bp
TUG1:15 chr22:31365698-31375382 8117 bp
TUG1:16 chr22:31365698-31375382 8103 bp
TUG1:17 chr22:31365698-31375382 8541 bp
TUG1:18 chr22:31365747-31375261 6829 bp
TUG1:19 chr22:31366663-31372049 2744 bp
TUG1:2 chr22:31365144-31369578 3291 bp
TUG1:20 chr22:31367034-31369414 1237 bp
TUG1:21 chr22:31367052-31374831 5123 bp
TUG1:22 chr22:31367052-31375381 5673 bp
TUG1:23 chr22:31367338-31369535 1248 bp
TUG1:24 chr22:31367353-31374831 4892 bp
TUG1:25 chr22:31367353-31372049 2110 bp
TUG1:26 chr22:31367408-31371991 1758 bp
TUG1:27 chr22:31367425-31369342 968 bp
TUG1:28 chr22:31367466-31369095 386 bp
TUG1:29 chr22:31367731-31369231 416 bp
TUG1:3 chr22:31365197-31375380 7541 bp
TUG1:30 chr22:31367912-31369598 1005 bp
TUG1:31 chr22:31368031-31375337 5057 bp
TUG1:32 chr22:31368249-31375377 5561 bp
TUG1:33 chr22:31368249-31372049 2233 bp
TUG1:34 chr22:31368887-31372067 1599 bp
TUG1:35 chr22:31369398-31371465 443 bp
TUG1:36 chr22:31365209-31369069 393 bp
TUG1:37 chr22:31365209-31375436 7502 bp
TUG1:38 chr22:31365209-31375436 7585 bp
TUG1:39 chr22:31365209-31381211 15053 bp
TUG1:4 chr22:31365197-31375380 7597 bp
TUG1:40 chr22:31365209-31381211 15053 bp
TUG1:41 chr22:31365255-31368924 695 bp
TUG1:42 chr22:31365255-31375372 5568 bp
TUG1:43 chr22:31365255-31375436 7863 bp
TUG1:44 chr22:31365255-31375436 7435 bp
TUG1:45 chr22:31365255-31381211 13143 bp
TUG1:46 chr22:31365476-31375391 8348 bp
TUG1:47 chr22:31365476-31375391 7652 bp
TUG1:48 chr22:31365476-31375391 5688 bp
TUG1:49 chr22:31365476-31375436 4968 bp
TUG1:5 chr22:31365197-31375380 7527 bp
TUG1:50 chr22:31365476-31375436 7589 bp
TUG1:51 chr22:31366642-31372049 2765 bp
TUG1:52 chr22:31368452-31372049 2030 bp
TUG1:53 chr22:31368452-31375446 5413 bp
TUG1:54 chr22:31368452-31375446 5427 bp
TUG1:55 chr22:31368876-31372067 1610 bp
TUG1:56 chr22:31365197-31375381 7542 bp
TUG1:57 chr22:31365197-31375381 7598 bp
TUG1:58 chr22:31365197-31375381 7528 bp
TUG1:59 chr22:31365231-31367469 375 bp
TUG1:6 chr22:31365229-31375194 7240 bp
TUG1:60 chr22:31365255-31374829 4650 bp
TUG1:61 chr22:31365256-31375381 7469 bp
TUG1:62 chr22:31365258-31374564 4214 bp
TUG1:63 chr22:31365264-31374817 4449 bp
TUG1:64 chr22:31365281-31372008 1817 bp
TUG1:65 chr22:31365458-31374834 5017 bp
TUG1:66 chr22:31365839-31371983 3419 bp
TUG1:67 chr22:31365918-31370089 3028 bp
TUG1:68 chr22:31365945-31374810 6154 bp
TUG1:69 chr22:31366080-31372044 3308 bp
TUG1:7 chr22:31365230-31375382 6716 bp
TUG1:70 chr22:31366168-31374833 7084 bp
TUG1:71 chr22:31366288-31374805 5875 bp
TUG1:72 chr22:31366676-31374809 5412 bp
TUG1:73 chr22:31366744-31372025 4207 bp
TUG1:74 chr22:31367050-31372100 2787 bp
TUG1:75 chr22:31367183-31369358 932 bp
TUG1:76 chr22:31367425-31374708 4752 bp
TUG1:8 chr22:31365262-31375327 5016 bp
TUG1:9 chr22:31365263-31375327 7422 bp


Locus conservation

Locus conservation?
TUG1 no no no no

Available literature

  1. Wang (2017), Long non-coding RNA TUG1 promotes migration and invasion by acting as a ceRNA of miR-335-5p in osteosarcoma cells., Cancer Sci.
  2. Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
  3. Ma (2016), Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma., Tumour Biol.
  4. Cai (2015), The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144., Oncotarget
  5. Hu (2015), Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus., Genes Dev.
  6. Huang (2015), Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2., Mol. Cancer
  7. Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Sci Rep
  8. Liu (2015), Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells., J. Neurooncol.
  9. Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proc. Natl. Acad. Sci. U.S.A.
  10. Sugihara (2015), Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma., Int J Mol Sci
  11. Tan (2015), Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells., FEBS Lett.
  12. Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
  13. Wang (2015), The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro., Biosci. Rep.
  14. Xu (2015), Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma., Tumour Biol.
  15. Yin (2015), Downregulation of lncRNA TUG1 affects apoptosis and insulin secretion in mouse pancreatic β cells., Cell. Physiol. Biochem.
  16. Gezer (2014), Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes., Cell Biol. Int.
  17. Isin (2014), Investigation of circulating lncRNAs in B-cell neoplasms., Clin. Chim. Acta
  18. Li (2014), Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Front Bioeng Biotechnol
  19. Michalik (2014), Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth., Circ. Res.
  20. Puvvula (2014), Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit., Nat Commun
  21. Roberts (2014), The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
  22. Wan (2014), Noncoding RNAs in DNA repair and genome integrity., Antioxid. Redox Signal.
  23. Zhang (2014), P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression., Cell Death Dis
  24. van Heesch (2014), Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes., Genome Biol.
  25. Cao (2013), Analysis of long non-coding RNA expression profiles in gastric cancer., World J. Gastroenterol.
  26. Chen (2013), Novel human lncRNA-disease association inference based on lncRNA expression profiles., Bioinformatics
  27. Han (2013), Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder., J Surg Oncol
  28. Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
  29. Liu (2013), WITHDRAWN: Down-regulation of long non-coding RNA TUG1 suppresses melanoma cell proliferation and induces apoptosis via up-regulating microRNA-9., Biochem. Biophys. Res. Commun.
  30. Liu (2013), Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA., RNA
  31. Sauvageau (2013), Multiple knockout mouse models reveal lincRNAs are required for life and brain development., Elife
  32. Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
  33. Zhang (2013), Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis., Asian Pac. J. Cancer Prev.
  34. Özgür (2013), Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells., Clin. Exp. Med.
  35. Clark (2012), Genome-wide analysis of long noncoding RNA stability., Genome Res.
  36. Jalali (2012), Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs., Biol. Direct
  37. Johnson (2012), Long non-coding RNAs in Huntington's disease neurodegeneration., Neurobiol. Dis.
  38. Kelley (2012), Transposable elements reveal a stem cell-specific class of long noncoding RNAs., Genome Biol.
  39. Tani (2012), Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals., Genome Res.
  40. Friedel (2009), Conserved principles of mammalian transcriptional regulation revealed by RNA half-life., Nucleic Acids Res.
  41. Guttman (2009), Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals., Nature
  42. Khalil (2009), Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression., Proc. Natl. Acad. Sci. U.S.A.
  43. Young (2005), The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina., Curr. Biol.