Transcript: TUG1:13

Basic information

LNCipedia transcript ID: TUG1:13 
LNCipedia gene ID: TUG1
Location (hg19): chr22:31365698-31375382
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 7167 bp
Exons: 4
Sources: Sun and Gadad et al., 2015
Alternative transcript names: LncRNA916:3
Alternative gene names: FLJ20618; NCRNA00080; LINC00080


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites non-coding 
PhyloCSF score -124.9389 non-coding 
CPAT coding probability 1.63% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
TUG1:13 no no no no

Available literature

  1. Wang (2017), Long non-coding RNA TUG1 promotes migration and invasion by acting as a ceRNA of miR-335-5p in osteosarcoma cells., Cancer Sci.
  2. Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
  3. Ma (2016), Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma., Tumour Biol.
  4. Cai (2015), The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144., Oncotarget
  5. Hu (2015), Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus., Genes Dev.
  6. Huang (2015), Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2., Mol. Cancer
  7. Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Sci Rep
  8. Liu (2015), Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells., J. Neurooncol.
  9. Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proc. Natl. Acad. Sci. U.S.A.
  10. Sugihara (2015), Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma., Int J Mol Sci
  11. Tan (2015), Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells., FEBS Lett.
  12. Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
  13. Wang (2015), The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro., Biosci. Rep.
  14. Xu (2015), Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma., Tumour Biol.
  15. Yin (2015), Downregulation of lncRNA TUG1 affects apoptosis and insulin secretion in mouse pancreatic β cells., Cell. Physiol. Biochem.
  16. Gezer (2014), Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes., Cell Biol. Int.
  17. Isin (2014), Investigation of circulating lncRNAs in B-cell neoplasms., Clin. Chim. Acta
  18. Li (2014), Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Front Bioeng Biotechnol
  19. Michalik (2014), Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth., Circ. Res.
  20. Puvvula (2014), Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit., Nat Commun
  21. Roberts (2014), The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
  22. Wan (2014), Noncoding RNAs in DNA repair and genome integrity., Antioxid. Redox Signal.
  23. Zhang (2014), P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression., Cell Death Dis
  24. van Heesch (2014), Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes., Genome Biol.
  25. Cao (2013), Analysis of long non-coding RNA expression profiles in gastric cancer., World J. Gastroenterol.
  26. Chen (2013), Novel human lncRNA-disease association inference based on lncRNA expression profiles., Bioinformatics
  27. Han (2013), Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder., J Surg Oncol
  28. Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
  29. Liu (2013), WITHDRAWN: Down-regulation of long non-coding RNA TUG1 suppresses melanoma cell proliferation and induces apoptosis via up-regulating microRNA-9., Biochem. Biophys. Res. Commun.
  30. Liu (2013), Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA., RNA
  31. Sauvageau (2013), Multiple knockout mouse models reveal lincRNAs are required for life and brain development., Elife
  32. Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
  33. Zhang (2013), Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis., Asian Pac. J. Cancer Prev.
  34. Özgür (2013), Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells., Clin. Exp. Med.
  35. Clark (2012), Genome-wide analysis of long noncoding RNA stability., Genome Res.
  36. Jalali (2012), Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs., Biol. Direct
  37. Johnson (2012), Long non-coding RNAs in Huntington's disease neurodegeneration., Neurobiol. Dis.
  38. Kelley (2012), Transposable elements reveal a stem cell-specific class of long noncoding RNAs., Genome Biol.
  39. Tani (2012), Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals., Genome Res.
  40. Friedel (2009), Conserved principles of mammalian transcriptional regulation revealed by RNA half-life., Nucleic Acids Res.
  41. Guttman (2009), Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals., Nature
  42. Khalil (2009), Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression., Proc. Natl. Acad. Sci. U.S.A.
  43. Young (2005), The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina., Curr. Biol.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
4.0 TUG1:13
4.1 TUG1:13
5.0 TUG1:13
5.1 TUG1:13
5.2 TUG1:13